Author

Yufeng Wang

Brigham and Women's HospitalORCID 0000-0002-8585-6996Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yufeng Wang2 papers · Peking University

Biology Disciplines

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Bioengineering· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jonathan V. RocheleauiD· 2 shared Nitya GulatiiD· 2 shared Adriana MiglioriniiD· 1 shared Ali H. AlhasaniD· 1 shared Amanda OakieiD· 1 shared Bhingaradiya NutaniD· 1 shared Chetan Shukla· 1 shared Dana Wu· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

Jonathan V. RocheleauORCID

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3 papers

Recent·Most cited

BioengineeringProceedings of the National Academy of SciencesPeer-reviewedMar 31, 2025

A Mechanically Resilient Soft Hydrogel Improves Drug Delivery for Treating Post-Traumatic Osteoarthritis in Physically Active Joints

Nitin Joshi, Jing Yan, Mickael Dang…·Joerg Ermann

This paper develops a mechanically resilient hydrogel for drug delivery in physically active joints, showing sustained release and reduced cartilage degeneration in a mouse model of post-traumatic osteoarthritis.

26 citationstop 3%

mouseexperimental assay

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BioengineeringACS OmegaPeer-reviewedMar 13, 2025

Development of an on-chip fluorescence anisotropy immunoassay for human C-peptide secretion reveals a general roadmap for tracer optimization

Yufeng Wang, Nitya Gulati, Romario Regeenes…·Jonathan V. Rocheleau

The paper develops an on-chip fluorescence anisotropy immunoassay for human C-peptide by optimizing antibody-tracer pairs to achieve high sensitivity and fast kinetics for microfluidic measurement.

2 citations

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ImmunologyPLoS ONEPeer-reviewedMar 5, 2025

Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response

Kenneth K. Y. Ting, Hisham M. Ibrahim, Nitya Gulati…·Myron I. Cybulsky

This study shows that free cholesterol accumulation in macrophages activates a PARP1 response to DNA damage, which suppresses lipopolysaccharide-induced inflammation through a non-enzymatic mechanism.

8 citations

mousebulk RNA-seq

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