Author

Skyler Friedline

University of British ColumbiaORCID 0000-0002-1027-7631Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam M. DeutschbaueriD· 1 shared Adam P. ArkiniD· 1 shared Anthony J. AbeliD· 1 shared Chathuri Jeewanthi Kombala Nanayakkara ThambiliyaiD· 1 shared Danielle GoudeauiD· 1 shared Douglas S. ClarkiD· 1 shared Elizabeth McDanieliD· 1 shared Heather M. OlsoniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Adam M. DeutschbauerORCID

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2 papers

Recent·Most cited

Activity-targeted metaproteomics uncovers rare syntrophic bacteria central to anaerobic community metabolism

Skyler Friedline, Elizabeth McDaniel, Matthew Scarborough, Maxwell Madill, Kate Waring, Vivian Lin, Rex R. Malmstrom, Danielle Goudeau, William Chrisler, Morten Simonsen Dueholm, Leo J. Gorham, Chathuri Jeewanthi Kombala Nanayakkara Thambiliya, Lydia H. Griggs, Heather M. Olson, Sophie Lehmann, , Ryan M. Ziels

The paper uses activity-targeted metaproteomics to study rare syntrophic bacteria in anaerobic communities, revealing their metabolic activity and a previously hypothesized oxidative glycine pathway.

Nature Microbiology · Oct 21, 2025Peer-reviewedMicrobiology

Eliminating Genes for a Two Component System Increases PHB Productivity in Cupriavidus basilensis 4G11 Under PHB Suppressing, Non-Stress Conditions

Kyle B. Sander, Anthony J. Abel, Skyler Friedline, William A. Sharpless, Jeffrey M. Skerker, Adam M. Deutschbauer, Douglas S. Clark, Adam P. Arkin

This study identifies two genes in a two-component system whose deletion increases PHB productivity in Cupriavidus basilensis under non-stress conditions.

Biotechnology and Bioengineering · Aug 28, 2023Peer-reviewedGenomics