Activity-targeted metaproteomics uncovers rare syntrophic bacteria central to anaerobic community metabolism
Skyler Friedline, Elizabeth McDaniel, Matthew Scarborough, Maxwell Madill, Kate Waring, Vivian Lin, Rex R. Malmstrom, Danielle Goudeau, William Chrisler, Morten Simonsen Dueholm, Leo J. Gorham, Chathuri Jeewanthi Kombala Nanayakkara Thambiliya, Lydia H. Griggs, Heather M. Olson, Sophie Lehmann, , Ryan M. Ziels
The paper uses activity-targeted metaproteomics to study rare syntrophic bacteria in anaerobic communities, revealing their metabolic activity and a previously hypothesized oxidative glycine pathway.
Nature Microbiology · Oct 21, 2025Peer-reviewedMicrobiology