Mark S. Ladinsky

The paper identifies extensive membrane contact sites between the mealybug endosymbiont Tremblaya and host mitochondria, suggesting these interactions provide essential membrane and metabolic components.

The paper develops a multimodal imaging pipeline to enable cryo-ET of symbiotic tissues, revealing nanoscale structural details of host-microbe interactions in Hawaiian bobtail squid.

This study shows that PPARγ downregulation in colonic CD8+ T cells of people with HIV on ART leads to epithelial barrier disruption by promoting lipid uptake and apoptosis.

The paper identifies a mutation in the SARS-CoV-2 nucleocapsid protein that enhances viral infection by promoting dimer formation and altering virion structure.

The paper shows that separated N- and C-terminal parts of Ana1 can rescue centriole duplication but not elongation, highlighting distinct functional requirements for Ana1 in these processes.

The paper uses electron tomography to visualize HIV-1 virions trapped by fusion inhibitors in infected tissues, revealing pre-hairpin intermediates linked to host cells.