Transcriptional networks predating cognition-associated pyramidal lineages are restructured by erythropoietin
Manvendra Singh, Ying Zhao, Vinícius Daguano Gastaldi, Sonja M. Wojcik, Yasmina Curto, Riki Kawaguchi, Ricardo Martins Merino, Laura Fernandez Garcia‐Agudo, Holger Taschenberger, Nils Brose, Daniel H. Geschwind, Klaus‐Armin Nave, Hannelore Ehrenreich
This study uses single-nucleus RNA sequencing to show that erythropoietin treatment restructures transcriptional networks in hippocampal pyramidal neurons, increasing their numbers and altering gene expression related to neurodifferentiation and cognition.
bioRxiv · Feb 4, 2023 · PreprintNeuroscience