Holger Taschenberger

This study investigates how Neuroligin-2 interacts with MDGA1 and MDGA2 to regulate gephyrin aggregation and GABAAR function in mouse hippocampal synapses, revealing MDGA1's role in modulating these processes.

This study shows that LTP at layer 5 pyramidal neurons increases synaptic strength by increasing the number of fully-primed, slowly-recovering vesicles.

This study uses single-nucleus RNA sequencing to show that erythropoietin treatment restructures transcriptional networks in hippocampal pyramidal neurons, increasing their numbers and altering gene expression related to neurodifferentiation and cognition.

This study shows that presynaptic Rac1 regulates synaptic strength by controlling synaptic vesicle priming and release probability in mouse calyx of Held synapses.

This study identifies de novo missense variants in SLC32A1 as a cause of a neurodevelopmental disorder with epilepsy, showing they impair GABAergic neurotransmission through two mechanisms.

The paper demonstrates a two-step priming scheme that reproduces synaptic strength and short-term plasticity diversity using non-negative tensor factorization and state modeling.