NeuroscienceJCI InsightPeer-reviewed
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors
Paul Dembny, Andrew G. Newman, Manvendra Singh…·Seija Lehnardt
This study shows HERV-K(HML-2) RNA activates TLR8 and Tlr7, causing neurodegeneration in mice and correlating with AD in humans.