Author

Douglas Taylor Golenbock

University of Massachusetts Chan Medical SchoolORCID 0000-0002-2447-2358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Christina KrügeriD· 2 shared Gunnar KleinauiD· 2 shared Patrick ScheereriD· 2 shared Seija LehnardtiD· 2 shared Adrian R. OrszulakiD· 1 shared Aimee J. AylwardiD· 1 shared Andrew G. NewmaniD· 1 shared Benjamin P. Readhead· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Christina KrügerORCID

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Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 3, 2026

Cellular nucleic acid-binding protein (CNBP) dependent cytokine programming shapes host defense against Plasmodium infection

Romana Rashid, Leandro de Souza Silva, Shahid Banday…·Douglas Taylor Golenbock

This study identifies CNBP's role in regulating the IL12β-IFN-γ axis during Plasmodium infection, showing its importance in immune control and potential as a therapeutic target.

DOI 10.64898/2026.06.01.729202

mousehuman

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Genomicsnpj DementiaPeer-reviewedMar 9, 2026

Development of a high-throughput, quantitative platform using human cerebral organoids to study virus-induced neuroinflammation in Alzheimer's disease

Meagan N. Olson, Pepper Dawes, Liam F. Murray…·Elaine T. Lim

This study develops a high-throughput platform using human cerebral organoids to screen for compounds that reverse HSV-1-induced neuroinflammation biomarkers associated with Alzheimer's disease.

8 citationstop 1%

humanexperimental assay

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ImmunologybioRxivPreprintOct 14, 2025

Murine Toll-like receptor 8 is a functional sensor of nucleic acid fragments

Lukas Hinkelmann, Mariam Brehm, Victor Wumbor-Apin Kumbol…·Seija Lehnardt

This study shows that murine TLR8 is a functional nucleic acid sensor, responding to synthetic and endogenous ligands and restoring TLR7-dependent transcriptional programs in vivo.

2 citations

mouseexperimental assay

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NeuroscienceJCI InsightPeer-reviewedApr 8, 2020

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

Paul Dembny, Andrew G. Newman, Manvendra Singh…·Seija Lehnardt

This study shows HERV-K(HML-2) RNA activates TLR8 and Tlr7, causing neurodegeneration in mice and correlating with AD in humans.

134 citationstop 2%

humanmouse

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