Author

Michael P. Rettig

Washington University in St. LouisORCID 0000-0002-1091-0564Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

John F. DiPersioiD· 2 shared Adeeb H. Rahmman· 1 shared Aditya R. YelamaliiD· 1 shared Aishwarya KrishnaniD· 1 shared Alessandro LaganàiD· 1 shared Andrew HoustoniD· 1 shared Andrew L. YoungiD· 1 shared April Cook· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenomics

John F. DiPersioORCID

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3 papers

Recent·Most cited

JARID2 Inhibition Reprograms Human Hematopoietic Progenitor Cells To Enhance Bone Marrow Transplantation

Wentao Han, Hassan Bjeije, Hamza Celik, Michael P. Rettig, Nancy Issa, Andrew L. Young, Yanan Li, Infencia Xavier Raj, Christine R. Zhang, Aishwarya Krishnan, Tyler M. Parsons, Samantha C. Burkart, Jason Arand, Wei Yang, Jeffrey A. Magee, Grant Anthony Challen

JARID2 inhibition enhances repopulating activity of human hematopoietic stem and progenitor cells in vivo via STAT1 upregulation.

Blood Advances · Jul 23, 2026Peer-reviewedDevelopmental Biology

A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

William Pilcher, Lijun Yao, Edgar Gonzalez‐Kozlova, Yered H. Pita-Juárez, Dimitra Karagkouni, Chaitanya R. Acharya, Marina E. Michaud, Mark Hamilton, Shivani Nanda, Yizhe Song, Kazuhito Sato, Julia T. Wang, Sarthak Satpathy, Yuling Ma, Jessica Schulman, , Manoj Bhasin

The paper characterizes immune microenvironment dysregulation in multiple myeloma using single-cell data and links it to disease progression and patient outcomes.

Nature Cancer · Jan 9, 2026Peer-reviewedGenomics

Streptavidin-drug conjugates streamline optimization of antibody-based conditioning for hematopoietic stem cell transplantation

Aditya R. Yelamali, Ezhilarasi Chendamarai, Julie Ritchey, Michael P. Rettig, John F. DiPersio, Stephen P. Persaud

This paper develops a streptavidin-drug conjugate platform to efficiently optimize antibody-based conditioning for HSCT, finding that PBD dimer SGD-1882 is most effective for targeting HSCs and AML cells.

Blood Immunology & Cellular Therapy · Oct 7, 2025Peer-reviewedImmunology