Marina Scardigli

The paper investigates the combined inotropic effects of SERCA2a stimulation and myofilament Ca2+ sensitization in murine myocardium, finding limited responsiveness to LEVO compared to human myocardium.

This paper uses polarized second-harmonic generation microscopy to analyze myosin states in hypertrophic cardiomyopathy, showing increased ON state fraction in mutated tissue.

The paper demonstrates that cardiac myocyte T-tubules can generate action potentials autonomously, distinct from those in the sarcolemma, using an all-optical method.

This paper introduces a semi-supervised segmentation model for identifying supragranular and infragranular layers in human cerebral cortex MRI scans with high precision.

This paper develops a method to 3D molecularly characterize cleared human brain tissues using light-sheet fluorescence microscopy.

The paper develops an imaging pipeline to create a cell census of the human cerebral cortex using MRI, immunohistochemistry, and light-sheet fluorescence microscopy.

The paper presents a method combining immunostaining, SWITCH/TDE clearing, and confocal microscopy to map neurons in human cerebral cortex slices, addressing challenges in labeling and clearing.