Bernd Krämer

Investigation of the Role of the LC3 Conjugation System in Autophagy for Human Reward System Reactivity

The paper investigates how variations in the LC3 conjugation system affect reward system reactivity in humans using fMRI and genetic analysis.

Lifestyle, Early-life, and Genetic Health Risk Factors Underlying the Brain Age Gap: A Mega-Analysis Across 3,934 Individuals from the ENIGMA MDD Consortium

This study identifies lifestyle, early-life, and genetic factors associated with brain age gaps in individuals with major depressive disorder compared to controls.

Dissecting heterogeneity in cortical thickness abnormalities in major depressive disorder: a large-scale ENIGMA MDD normative modelling study

This study uses normative modeling to analyze cortical thickness deviations in MDD patients and healthy controls, finding large overlaps and significant heterogeneity in extreme deviations across individuals.

DNAJC13 influences responses of the extended reward system to conditioned stimuli: a genome-wide association study

This study identifies a genetic variant in DNAJC13 that influences neural activation in the reward system in response to conditioned stimuli using GWAS and fMRI.

Gene Set-Based Analysis of the Endosomal Sorting Processes Cargo Selection and Membrane Tubulation with Human Reward System Reactivity

The paper investigates how genetic variations affecting endosomal sorting processes influence neural responses in the reward system using fMRI and gene set analysis.

Greater male than female variability in regional brain structure across the lifespan

The paper analyzes sex differences in brain structure variability across the lifespan using a large dataset, finding greater male variability in subcortical volumes, cortical surface area, and thickness in most regions.

Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

This paper examines brain aging in major depressive disorder (MDD) using a large dataset, finding that MDD patients show increased brain age differences compared to controls.

The genetic architecture of the human cerebral cortex

The paper identifies genetic loci associated with human cortical structure and finds genetic correlations with neuropsychiatric disorders.

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

The paper identifies 25 genetic loci associated with subcortical brain structure volumes in over 40,000 individuals, revealing novel biology and potential drug targets.