Author

Ridao Chen

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-1151-8804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:plant (other)· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexey SilakoviD· 1 shared Amie K. BoaliD· 1 shared Binju WangiD· 1 shared Carsten KrebsiD· 1 shared Changkang LiiD· 1 shared Dawei CheniD· 1 shared Eliott S. WengeriD· 1 shared J ZHANGiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Alexey SilakovORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 6, 2026

Missing taxane C13α-O-deacetylases reveal a cryptic acetylation-deacetylation module in paclitaxel biosynthesis

Changkang Li, Xincheng Sun, Ridao Chen…·Jungui Dai

The paper identifies and characterizes two novel C13-O-deacetylases and a C7β-O-deacetylase, demonstrating their role in paclitaxel biosynthesis and enabling a more efficient 19-gene pathway for baccatin III production.

DOI 10.64898/2026.04.28.721278

plant (other)experimental assay

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BiochemistrybioRxivPreprintJun 3, 2026

Metal Coordination Dynamics Governs Selective Epoxidation in Hyoscyamine 6β-Hydroxylase: Integrated Experimental and Computational Insights

J ZHANG, Lian Wu, Siqi Wu…·Binju Wang

This paper investigates the catalytic mechanism of hyoscyamine 6β-hydroxylase, revealing that metal coordination dynamics govern selectivity between hydroxylation and epoxidation reactions.

DOI 10.64898/2026.06.01.729211

statistical modelchromatin & epigenetic regulation

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