Author

Amie K. Boal

Pennsylvania State UniversityORCID 0000-0002-1234-8472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Carsten KrebsiD· 2 shared Alexey SilakoviD· 1 shared Binju WangiD· 1 shared Eliott S. WengeriD· 1 shared J ZHANGiD· 1 shared Jay V. PendyalaiD· 1 shared Jiahai Zhou· 1 shared Joseph Martin Bollinger Jr.iD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Carsten KrebsORCID

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2 papers

Recent·Most cited

BiochemistryACS Bio & Med Chem AuPeer-reviewedAug 5, 2026

Amino Acids in the RSSY Motif of Lipoyl Synthase Control Substrate Binding and Reactivity

Vivian Robert Jeyachandran, Nicholas D. Lanz, Maria‐Eirini Pandelia…·Squire J. Booker

This paper investigates the role of amino acids in the RSSY motif of lipoyl synthase, showing that Arg306 and Ser308 are critical for substrate binding and catalytic activity, with specific substitutions affecting product formation and cluster stability.

DOI 10.1021/acsbiomedchemau.6c00105

E. coliexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJun 3, 2026

Metal Coordination Dynamics Governs Selective Epoxidation in Hyoscyamine 6β-Hydroxylase: Integrated Experimental and Computational Insights

J ZHANG, Lian Wu, Siqi Wu…·Binju Wang

This paper investigates the catalytic mechanism of hyoscyamine 6β-hydroxylase, revealing that metal coordination dynamics govern selectivity between hydroxylation and epoxidation reactions.

DOI 10.64898/2026.06.01.729211

statistical modelchromatin & epigenetic regulation

𝕏 PostBluesky