Author

Zoeb Jiwaji

Edinburgh Royal InfirmaryORCID 0000-0002-3129-1168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Giles E. HardinghamiD· 2 shared Owen DandoiD· 2 shared Siddharthan ChandraniD· 2 shared Áine Bríd HeffernaniD· 1 shared Amy F. LloydiD· 1 shared Andrew J.M. HowdeniD· 1 shared Anna WilliamsiD· 1 shared Ayisha MahmoodiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Giles E. HardinghamORCID

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3 papers

Recent·Most cited

Integrated genomic meta-analysis identifies cell-type-specific signatures and targets in early Alzheimer's disease

Moritz Steinruecke, John Kenneth Baillie, Zoeb Jiwaji

This study integrates multiomic data to identify cell-type-specific pathways and therapeutic targets in early Alzheimer's disease.

medRxiv · Sep 23, 2026 · PreprintGenetic & Genomic Medicine

Astrocytes control motor neuronal mitochondrial axonal transport deficits in C9ORF72 ALS.

Maria Stavrou, Áine Bríd Heffernan, Roderick N. Carter, Owen Dando, Zoeb Jiwaji, Karen Burr, Jyoti Nanda, Justyna Cholewa-Waclaw, David Story, Giles E. Hardingham, Siddharthan Chandran, Bhuvaneish T. Selvaraj

This study shows that C9ORF72-mutant astrocytes disrupt axonal transport in motor neurons, and correcting this rescues transport deficits.

bioRxiv · Jun 10, 2025 · PreprintNeuroscience

Astrocyte-Oligodendrocyte interaction regulates central nervous system regeneration

Irene Molina-González, Rebecca K. Holloway, Zoeb Jiwaji, Owen Dando, Sarah A. Kent, Katie Emelianova, Amy F. Lloyd, Lindsey H. Forbes, Ayisha Mahmood, Thomas Skripuletz, Viktoria Gudi, James A. Febery, Jeffrey Allan Johnson, Jill H. Fowler, Tanja Kuhlmann, , Véronique E. Miron

The paper shows that astrocyte-oligodendrocyte interaction is critical for remyelination and identifies a drug strategy targeting this interaction to promote central nervous system regeneration.

Nature Communications · Jun 8, 2023Peer-reviewedNeuroscience