Yingyu Chen

This study identifies MmpE as a nucleomodulin in Mycobacterium tuberculosis that inhibits host inflammatory gene expression and promotes intracellular survival by targeting the VDR promoter and regulating the PI3K-Akt-mTOR pathway.

This study identifies MgdE, a mycobacterial nucleomodulin, as a protein that targets the host COMPASS complex to suppress pro-inflammatory gene transcription and enhance bacterial survival.

This study identifies RBMX2 as a host factor that enhances M. bovis infection and drives infection-induced epithelial-mesenchymal transition, linking TB to lung cancer progression.