Author

Liu Chen

Huazhong Agricultural UniversityORCID 0009-0003-3722-6994Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Liu Chen1 paper · Harvard University

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1

Frequent Co-Authors

Aizhen GuoiD· 2 shared Baojie Duan· 2 shared Lei ZhangiD· 2 shared Qiang JiangiD· 2 shared Yingyu CheniD· 2 shared Changmin HuiD· 1 shared Lu Lu· 1 shared Pingping Chen· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Aizhen GuoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologybioRxivJun 24, 2025

Mycobacterial Metallophosphatase MmpE Acts as a Nucleomodulin to Regulate Host Gene Expression and Promote Intracellular Survival

Liu Chen, Baojie Duan, Qiang Jiang…·Aizhen Guo

This study identifies MmpE as a nucleomodulin in Mycobacterium tuberculosis that inhibits host inflammatory gene expression and promotes intracellular survival by targeting the VDR promoter and regulating the PI3K-Akt-mTOR pathway.

1 citation

𝕏 PostBluesky

MicrobiologybioRxivMay 21, 2025

A Conserved Mycobacterial Nucleomodulin Hijacks the Host COMPASS Complex to Reprogram Pro-Inflammatory Transcription and Promote Intracellular Survival

Liu Chen, Baojie Duan, Pingping Chen…·Aizhen Guo

This study identifies MgdE, a mycobacterial nucleomodulin, as a protein that targets the host COMPASS complex to suppress pro-inflammatory gene transcription and enhance bacterial survival.

2 citations

𝕏 PostBluesky