Synthetic BiologybioRxivPreprint
Drug-Mediated Control of Receptor Valency Enhances Immune Cell Potency
Paul B. Finn, Michael Chavez, Xinyi Chen…·Lei S. Qi
This paper develops valency-controlled receptors (VCRs) to enhance CAR functionality by modulating T cell signaling through multivalent ligands, showing improved immune response against tumors.
2 citations