Author

Philip Bittihn

University of California San DiegoORCID 0000-0002-1276-9381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeff HastyiD· 2 shared Lev S. TsimringiD· 2 shared Alejandro JuradoiD· 1 shared Andriy DidovykiD· 1 shared Arne D. HofemeieriD· 1 shared Jonas IsenseeiD· 1 shared Lea Johanna KrügeriD· 1 shared Lorraine PillusiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersSynthetic Biology

Jeff HastyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

3D dynamic multiscale force and shape analysis of in-vivo elastic stress sensors

Alejandro Jurado, Jonas Isensee, Arne D. Hofemeier, Lea Johanna Krüger, Raphael Wittkowski, Ramin Golestanian, Philip Bittihn, Timo Betz

This paper introduces Bead-Buddy, a platform for rapid evaluation of deformation and stresses from fluorescently labelled sensors in vivo.

Biophysical Journal · Jul 22, 2025Peer-reviewedBiophysics

Engineered phenotype patterns in microbial populations

Philip Bittihn, Andriy Didovyk, Lev S. Tsimring, Jeff Hasty

This paper designs gene circuits to control spatiotemporal growth phenotype patterns in microbial colonies, demonstrating oscillations between growth and dormancy and enabling selective gene expression in non-dividing cells.

bioRxiv · Mar 13, 2019 · PreprintSynthetic Biology

Multi-generational silencing dynamics control cell aging

Yang Li, Meng Jin, Richard O’Laughlin, Philip Bittihn, Lev S. Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao

The paper tracks replicative aging in yeast cells and finds that intermittent heterochromatin silencing loss regulates lifespan, with Sir2 deacetylase playing a key role.

Proceedings of the National Academy of Sciences · Oct 3, 2017Peer-reviewedSystems Biology