Author

Emilee E. Shine

Princeton UniversityORCID 0000-0002-1290-2496Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Bonnie L. BassleriD· 3 shared Julie S. ValastyaniD· 2 shared Francis J. SantorielloiD· 1 shared Gabriel D. D’Agostino· 1 shared Jonathan Z. Huang· 1 shared Michael Bunsick· 1 shared Mohammad R. SeyedsayamdostiD· 1 shared Robert A. Mook· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

Bonnie L. BasslerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 3, 2026

Competing Inter-Domain Quorum-Sensing Systems Control Prophage Lysis-Lysogeny Decisions

Michael Bunsick, Gabriel D. D’Agostino, Thu Vu Phuc Nguyen…·Bonnie L. Bassler

The paper shows how prophages use quorum-sensing systems to compete with each other and the host, making lysis decisions based on autoinducer ratios.

DOI 10.64898/2026.07.02.736140

bacteria (other)experimental assay

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BiochemistryJournal of the American Chemical SocietyPeer-reviewedFeb 4, 2026

Discovery of a Human Metabolite that Mimics the Bacterial Quorum-Sensing Autoinducer AI-2

Emilee E. Shine, Julie S. Valastyan, Vanessa Y. Ying…·Bonnie L. Bassler

This study identifies L-xylosone as a human metabolite that mimics the bacterial quorum-sensing autoinducer AI-2, revealing a new host-microbe interaction.

4 citationstop 3%

humanmetabolomics

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MicrobiologyACS Chemical BiologyPeer-reviewedMay 14, 2025

Inhibitors of the PqsR Quorum-Sensing Receptor Reveal Differential Roles for PqsE and RhlI in Control of Phenazine Production

Julie S. Valastyan, Emilee E. Shine, Robert A. Mook, Bonnie L. Bassler

This study identifies PqsR inhibitors that reveal RhlR's dependence on PqsE for pyocyanin biosynthesis, suggesting PqsR inhibition as a therapeutic strategy against Pseudomonas aeruginosa.

12 citations

bacteria (other)experimental assay

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