Julie S. Valastyan

The paper identifies a double-negative feedback loop between LuxT and VqmR in V. cholerae that regulates quorum-sensing genes and biofilm formation.

This study determines the cryo-EM structures of CqsS and its interaction with CqsA and CAI-1, revealing the molecular mechanism of quorum-sensing signal transduction in Vibrio harveyi.

This study identifies L-xylosone as a human metabolite that mimics the bacterial quorum-sensing autoinducer AI-2, revealing a new host-microbe interaction.

This study identifies PqsR inhibitors that reveal RhlR's dependence on PqsE for pyocyanin biosynthesis, suggesting PqsR inhibition as a therapeutic strategy against Pseudomonas aeruginosa.