Author

Jeffrey S. Schorey

University of Notre DameORCID 0000-0002-1305-0651Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Alanna SedgwickiD· 1 shared Crislyn D’Souza-Schorey· 1 shared Crislyn D’Souza‐SchoreyiD· 1 shared Joseph A. VecchioiD· 1 shared Rose Nguyen· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Alanna SedgwickORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 24, 2026

Replication-deficient Adenovirus 5 Serotypes Induce Type I Interferon and enhance BCG-mediated Immune Response in Co-infected Murine Macrophages

Joseph A. Vecchio, Jeffrey S. Schorey

This study investigates how co-infection with replication-deficient adenovirus and BCG in murine macrophages affects type I interferon signaling and host-protective gene expression, showing additive immune responses despite BCG suppression of IFN induction.

DOI 10.64898/2026.06.24.734229

mousebulk RNA-seq

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Cancer BiologyJournal of Biological ChemistryPeer-reviewedJan 24, 2026

Large extracellular vesicles regulate endothelial angiogenic potential via paracrine and autocrine signaling

Crislyn D’Souza‐Schorey, Rose Nguyen, Alanna Sedgwick…·Crislyn D’Souza-Schorey

This study shows that large extracellular vesicles from melanoma promote angiogenic phenotypes in endothelial cells through paracrine and autocrine signaling, contributing to resistance to anti-angiogenic therapies.

DOI 10.1016/j.jbc.2026.111193

humanexperimental assay

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