Author

Crislyn D’Souza‐Schorey

University of Notre DameORCID 0000-0002-8389-055XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alanna SedgwickiD· 1 shared Crislyn D’Souza-Schorey· 1 shared Harikrishna NakshatriiD· 1 shared James W. ClancyiD· 1 shared Jeffrey S. SchoreyiD· 1 shared Madison SchmidtmanniD· 1 shared Rose Nguyen· 1 shared Victoria Elliott· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

Alanna SedgwickORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Biological ChemistryPeer-reviewedJan 24, 2026

Large extracellular vesicles regulate endothelial angiogenic potential via paracrine and autocrine signaling

Crislyn D’Souza‐Schorey, Rose Nguyen, Alanna Sedgwick…·Crislyn D’Souza-Schorey

This study shows that large extracellular vesicles from melanoma promote angiogenic phenotypes in endothelial cells through paracrine and autocrine signaling, contributing to resistance to anti-angiogenic therapies.

DOI 10.1016/j.jbc.2026.111193

humanexperimental assay

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Cancer BiologyiSciencePeer-reviewedMay 16, 2025

Ancestry-linked stromal variations impact breast epithelial cell invasion

Madison Schmidtmann, Victoria Elliott, James W. Clancy…·Crislyn D’Souza‐Schorey

The paper investigates how ancestry-linked stromal variations, specifically PZP cells, influence breast epithelial cell invasion in African and European ancestry individuals.

1 citation

humanbulk RNA-seq

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