Author

Ting Ran

Guangzhou LaboratoryORCID 0000-0002-1387-4634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Approach:graph neural network· 1

Frequent Co-Authors

Hongming CheniD· 4 shared Jinsai ShangiD· 3 shared Miru Tang· 3 shared Yongzhi LuiD· 3 shared Anqi ZhouiD· 2 shared Bao Xue· 2 shared Jielin TangiD· 2 shared Jinpeng Zhong· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

Hongming ChenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A novel AR molecular glue degrader via bivalent engagement of the N-terminal domain and RNF213-UBE2J2 complex

Kunzhong Wu, Qiong Wu, Yongzhi Lu, Qi Yang, Ting Ran, Jie Zhang, Xianjie Qiu, Chengjie Huang, Yue Lin, J K Chen, Z L Yang, Wei Qin, Zhu Liu, Xinqi Liu, Miru Tang, , Jinsai Shang

This paper introduces GZL626, a novel AR degrader that targets the N-terminal domain and RNF213-UBE2J2 complex, effectively degrading AR and AR-V7 and showing antitumor and antiviral activity.

bioRxiv · Jul 16, 2026 · PreprintBiophysics

Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19

Yongzhi Lu, Qi Yang, Ting Ran, Guihua Zhang, Weifeng Li, Peiqi Zhou, Jielin Tang, Minxian Dai, Jinpeng Zhong, Hua Chen, Pan He, Anqi Zhou, Bao Xue, Jiayi Chen, Jiyun Zhang, , Jinsai Shang

The paper identifies a potent orally bioavailable SARS-CoV-2 PLpro inhibitor with in vitro and in vivo antiviral activity against SARS-CoV-2 and related coronaviruses.

Nature Communications · Nov 23, 2024Peer-reviewedMicrobiology

Discovery of resistance-resilient quinoline papain-like protease inhibitors through topology-constrained molecular generative design

Yongzhi Lu, Ting Ran, Qi Yang, Guihua Zhang, Jiayi Chen, Peiqi Zhou, Wenqi Li, Minyuan Xu, Jielin Tang, Minxian Dai, Jinpeng Zhong, Hua Chen, Pan He, Anqi Zhou, Bao Xue, , Jinsai Shang

This paper discovers a novel quinoline-based PLpro inhibitor, GZNL-2016, that remains effective against drug-resistant SARS-CoV-2 variants like Omicron BA.5 and XBB.1.

bioRxiv · Sep 7, 2024 · PreprintMicrobiology

A Comprehensive Benchmark Study on Biomedical Text Generation and Mining with ChatGPT

Qijie Chen, Haotong Sun, Haoyang Liu, Yinghui Jiang, Ting Ran, Xurui Jin, Xianglu Xiao, Zhimin Lin, Zhangming Niu, Hongming Chen

This study evaluates ChatGPT's performance on biomedical text generation and mining tasks using various biomedical corpora.

bioRxiv · Apr 19, 2023 · PreprintBioinformatics