Author

Sean C. West

Integrated DNA Technologies (United States)ORCID 0000-0002-1394-1999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea Sánchez PeñaiD· 1 shared Ashley M. JacobiiD· 1 shared Bernice Thommandru· 1 shared Dario GhersiiD· 1 shared Ellen SchmaljohniD· 1 shared Garrett R. RettigiD· 1 shared Gavin KurganiD· 1 shared He ZhangiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Andrea Sánchez PeñaORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedAug 11, 2026

UNCOVERseq Enables Sensitive and Controlled Gene Editing Off-Target Nomination Across CRISPR-Cas Modalities and Systems

Kyle J. Kinney, Kun Jia, He Zhang…·Gavin Kurgan

UNCOVERseq is a workflow for sensitive off-target nomination in CRISPR-Cas editing, demonstrating superior performance across multiple modalities and systems.

5 citationstop 3%

humanCRISPR screen

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BioinformaticsPLoS Computational BiologyPeer-reviewedOct 25, 2019

Uncovering and characterizing splice variants associated with survival in lung cancer patients

Sean C. West, Sushil Kumar K, Surinder K. Batra…·Dario Ghersi

The paper develops a computational method to identify splice variants linked to patient survival in lung cancer and predicts rewired protein interactions, finding variants involved in DNA repair.

10 citations

humanbulk RNA-seq

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