Surinder K. Batra

This study shows that inhibiting CXCR2 can enhance gemcitabine's effectiveness in pancreatic cancer by overcoming resistance in both parental and gemcitabine-resistant cells.

The paper proposes a systems modeling workflow for knowledge discovery in proteomics datasets, applied to pancreatic ductal adenocarcinoma to identify translational targets and pathways.

This study evaluates combinations of PDAC biomarkers across multiple labs, finding improved sensitivity and specificity for early-stage detection compared to CA19-9 alone.

The paper develops a computational method to identify splice variants linked to patient survival in lung cancer and predicts rewired protein interactions, finding variants involved in DNA repair.

The paper re-evaluates the efficiency of a CRISPR-Cas9 method for generating conditional knockout alleles in mice, finding very low success rates and high rates of undesired alleles.