Themistoklis M. Tsarouchas

The paper identifies an injury-induced stem cell-like state in zebrafish ERGs that promotes regenerative neurogenesis through lin28a and clcf1.

This study shows that C9ORF72 deficiency in zebrafish causes retinal degeneration, including reduced thickness, gliosis, and neuronal loss, but not spinal cord pathology.

The paper uses synthetic CRISPR gRNAs and in vivo pre-screening to identify pro-regenerative genes in spinal cord injury, finding that tgfb1a promotes regeneration by controlling inflammation.

The paper shows that macrophage-mediated dynamic control of Il-1β and Tnf-α is essential for spinal cord regeneration in zebrafish.