Claire E. Gustafson

The paper identifies diverse human antibody-secreting cell subsets using multi-omic methods and shows their distinct functional and spatial characteristics.

PULSAR is a foundation model that integrates multi-scale biological data to predict disease and clinical outcomes in the human immune system.

This study uses multi-omic profiling to analyze immune cell dynamics in healthy adults over time, finding age-related transcriptional changes in T cells and impaired memory B cell responses in older adults.

The paper identifies immune alterations preceding rheumatoid arthritis onset and provides tools for dataset exploration.

CryoSCAPE enables scalable immune profiling using cryopreserved whole blood for multi-omic single cell and functional assays, demonstrating compatibility with high-throughput RNA sequencing and functional testing.

SPARROW integrates spatial transcriptomics and scRNA-seq to identify microenvironment zones and their influence on cell states and functions across tissues.