Masaaki Kuwajima

This study generates Synpo KO rats to investigate Synpo's role in synaptic plasticity, development, and behavior, finding reduced LTP and body stature effects.

This study investigates how perisynaptic astroglia interact with synapses during long-term potentiation and depression in the hippocampal dentate gyrus of rats.

This study shows that long-term potentiation (LTP) increases synaptic information storage capacity in adult rat hippocampus by expanding the range of synapse sizes and improving precision.

This study identifies age-related synapse loss and violation of the ultrastructural size principle in the marmoset dlPFC as factors underlying working memory impairment in aged individuals.

The paper introduces a method to measure synaptic information storage capacity (SISC) using 3DEM data from rat hippocampus and finds regional and LTP-dependent variations in SISC.

The paper describes a method to analyze ultrastructural changes in axons after optogenetic stimulation to induce L-LTP, revealing synapse-specific modifications at the nanoscale.