Boris V. Zemelman

This study evaluates three pan-inhibitory viral constructs in macaques to assess their efficacy in targeting inhibitory neurons and modulating neural activity.

The paper shows that a non-conducting Cav1.4 Ca2+ channel is essential for cone synaptogenesis, and its absence is compensated by Cav3 channels, leading to normal cone-mediated vision in knock-in mice.

The paper identifies balanced excitatory and inhibitory circuitry in primate sensory cortex that amplifies weak signals while maintaining fast dynamics.

This study identifies how glutamatergic and GABAergic projections from the entorhinal cortex bidirectionally control pattern separation and completion in the hippocampus, influencing context discrimination and generalization.

The paper investigates how early cerebellar perturbation affects thalamic development, finding that Purkinje cell loss strengthens cerebellothalamic synapses and alters thalamic activity.

The paper describes a method to analyze ultrastructural changes in axons after optogenetic stimulation to induce L-LTP, revealing synapse-specific modifications at the nanoscale.

SArKS identifies cell type-specific DNA regulatory sequences by smoothing differential expression scores over sequence and spatial similarity, outperforming existing methods in motif discovery.