Cheng‐Hui Lin

Mitochondrial Transplantation in the Eye: A Review and Evaluation of Surgical Approaches

This paper reviews mitochondrial transplantation for eye diseases and evaluates delivery methods, finding that different routes target distinct retinal areas and show feasibility for further study.

Induction of a Muller glial-specific protective pathway safeguards the retina from diabetes induced damage

This study identifies Muller glial cells as sensitive to diabetes and shows that Zfp36 expression in these cells can protect against diabetic retinopathy.

Mettl14-mediated m6A modification ensures the cell cycle progression of late-born retinal progenitor cells

The paper shows that Mettl14-mediated m6A modification is critical for cell cycle progression of late-born retinal progenitor cells, preventing cell cycle arrest and neuronal death.

iGWAS: image-based genome-wide association of self-supervised deep phenotyping of human medical images

The paper introduces iGWAS, a method using self-supervised deep learning to extract phenotypes from medical images for GWAS, finding new genetic loci related to retinal vessel development.

Cell type- and stage-specific expression of Otx2 is coordinated by a cohort of transcription factors and multiple cis-regulatory modules in the retina