Samir P. Patel

The paper investigates delayed glucose metabolism changes in APP/PS1 KI mice after closed-head injury, finding increased pyruvate and lactate labeling in cortex and hippocampus 8 months post-injury.

This paper reviews mitochondrial transplantation for eye diseases and evaluates delivery methods, finding that different routes target distinct retinal areas and show feasibility for further study.

This study shows astrocytes transfer mitochondria to neurons after TBI to support mitochondrial function in neuronal soma, dendrites, and axons but not synapses, and demonstrates therapeutic potential of exogenous mitochondrial transfer via extracellular vesicles.

This study shows that traumatic brain injury worsens mitochondrial dysfunction in APP/PS1 mice through time-dependent mechanisms, with sex differences in vulnerability.

This pilot study investigates the impact of mitochondrial transplantation on infectious disease progression in mice, finding improved survival and reduced inflammation in sepsis models but not in influenza models.