Author

Murugesan V. S. Rajaram

The Ohio State UniversityORCID 0000-0002-1515-1122Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Naresh KumariD· 3 shared Latha Prabha GanesaniD· 2 shared Sameer Salam Matoo· 2 shared William P. LafuseiD· 2 shared Aakash Shah· 1 shared Adriana ForeroiD· 1 shared Alison Thomas· 1 shared Benjamin Douglas Xun LiuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Naresh KumarORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Age Dependent Immunopathology Drives Pneumonia-Associated Cardiac Dysfunction During Streptococcus pneumoniae Infection

Sameer Salam Matoo, Naresh Kumar, Mariam A. Salem, Alison Thomas, Aakash Shah, Pankaj Kumar, Miqdad O. Dhariwala, Liao Zhiwei, Haitao Wen, Stephanie Sevaue, Latha Prabha Ganesan, William P. Lafuse, Rachael Philips, Patrick L. Collins, Murugesan V. S. Rajaram

This study shows aging worsens cardiac dysfunction during Streptococcus pneumoniae infection through inflammation and impaired immune responses, with potential therapeutic targets identified.

bioRxiv · May 21, 2026 · PreprintImmunology

Pseudomonas aeruginosa-mediated cardiac dysfunction is driven by extracellular vesicles released during infection

Naresh Kumar, Sameer Salam Matoo, Shridhar Kiran Sanghvi, Maneeth Ellendula, Sahil Mahajan, Clara Planner, Joseph S. Bednash, Mahmood Khan, Latha Prabha Ganesan, Harpreet Singh, William P. Lafuse, Daniel J. Wozniak, Murugesan V. S. Rajaram

This study identifies extracellular vesicles from Pseudomonas aeruginosa-infected macrophages as drivers of cardiac dysfunction in cardiomyocytes.

mBio · Jan 15, 2026Peer-reviewedImmunology

Cardioprotective effects of AMPK activation in H1N1 influenza virus infection

Steve Leumi, Matthew I. McFadden, Naresh Kumar, Sameer Salam Mattoo, Jack E. Roettger, Samuel Speaks, Benjamin Douglas Xun Liu, Shreenath Mohan, Brendan M. Reznik, Jana M. Cable, Parker J. Denz, Murugesan V. S. Rajaram, Adriana Forero, Jacob S. Yount

This study shows that activating AMPK in mice infected with a modified H1N1 virus reduces cardiac damage by restoring mitochondrial function and improving survival.

bioRxiv · Aug 28, 2025 · PreprintMicrobiology