Joel A. Malek

This study identifies selective sweeps in SOS pathway genes of date palm genomes, suggesting adaptation to salinity through genetic changes.

The paper presents a gap-free, telomere-to-telomere genome assembly for date palm and 19 high-quality assemblies, revealing chromosomal structures and sex determination regions.

The paper introduces AVA-Seq, a method using long-read sequencing to detect full-length protein-protein interactions, achieving a 28.6% recovery rate on a gold standard dataset.

This study identifies genetic loci and candidate genes associated with date palm fruit size traits using GWAS and phenotypic data from diverse cultivars.

This study identifies genetic loci associated with fruit skin separation in date palm, showing both environmental and genetic contributions to the phenotype.

This study identifies genetic loci associated with dry date fruit color using genome sequences and image data from 199 samples.

The paper identifies novel interactions between the APC protein and Wnt-pathway nuclear transcription factors, suggesting APC may repress CTNNB1 through transcription factor binding.

The paper tests AVA-Seq on a human PPI reference set, finding it recovers 43% of binary PPIs and identifies novel interactions.

This study shows that circNFATc3 affects cancer cell proliferation, migration, and oxidative phosphorylation through gain and loss of function experiments.

The paper identifies genetic variants that control circular RNA expression by analyzing circRNA and genome sequence variation in lymphoblastoid cell lines from the 1000 Genomes Project.

This paper introduces AVA-seq, a method using next-generation sequencing to map protein-protein interactions with high resolution, demonstrating its application on human proteins.

This study compares 3D and 2D ovarian cancer models to show TGF-β induces EMT, invasion, and aggressiveness, with reversible effects using a TGF-β inhibitor.

The paper identifies four conserved genes in male date palms, supporting a two-mutation model for the evolution of dioecy from hermaphroditism.

The paper performs a GWAS on blood plasma proteome data from two cohorts to identify SNP-protein associations linked to various diseases and creates a genome-proteome network and web tool for analysis.