Julia C. van Kessel

This study identifies how CAP and LuxR co-regulate gene expression in Vibrio campbellii through synergistic or antagonistic promoter occupancy, revealing indirect regulation of bioluminescence.

This study shows that flagellar integrity influences quorum sensing in Vibrio species by bypassing cell-density regulation through the FlrBC system.

This study identifies four T3SS-secreted effectors in V. campbellii that exhibit cytotoxicity in eukaryotic cells, highlighting conserved T3SS structure but variable effector repertoires across the Harveyi clade.

This study identifies PTSP as a ligand that induces proteolytic degradation of SmcR, controlling quorum sensing state transitions in Vibrio species.

This study identifies a dual regulatory mechanism by LuxR in Vibrio campbellii that represses T3SS gene expression through transcriptional and post-translational repression of ExsA activity.

This study identifies an active quorum sensing pathway in Vibrio coralliilyticus that regulates virulence factors like proteases, biofilms, and type VI secretion systems.

This study identifies two temperature-regulated T6SSs in Vibrio coralliilyticus, revealing their roles in bacterial competition and host toxicity, with T6SS2 secreting nine novel anti-eukaryotic toxins.

The paper introduces Mobile-CRISPRi, a system for gene knockdown in Vibrio species, showing it effectively modulates gene expression and phenotypes.

The paper introduces RAIL, a method for constructing promoter-reporter libraries in Vibrio harveyi to identify promoter boundaries and regulatory sequences.