Ram Podicheti

This study shows that H3K9 methyltransferases regulate cortical growth by controlling heterochromatin formation and neural progenitor dynamics, leading to microcephaly when disrupted.

This study identifies how CAP and LuxR co-regulate gene expression in Vibrio campbellii through synergistic or antagonistic promoter occupancy, revealing indirect regulation of bioluminescence.

This study identifies four T3SS-secreted effectors in V. campbellii that exhibit cytotoxicity in eukaryotic cells, highlighting conserved T3SS structure but variable effector repertoires across the Harveyi clade.

This study identifies a dual regulatory mechanism by LuxR in Vibrio campbellii that represses T3SS gene expression through transcriptional and post-translational repression of ExsA activity.

This study identifies an active quorum sensing pathway in Vibrio coralliilyticus that regulates virulence factors like proteases, biofilms, and type VI secretion systems.

This study identifies two temperature-regulated T6SSs in Vibrio coralliilyticus, revealing their roles in bacterial competition and host toxicity, with T6SS2 secreting nine novel anti-eukaryotic toxins.

The paper evaluates HAND2 gene regulatory networks in endocardial cells using single-cell transcriptomics to identify HAND2-dependent enhancers and their impact on cardiac morphogenesis.

The paper performs transcriptome-wide pseudouridylation analysis in Drosophila melanogaster, identifying thousands of Psi modifications across rRNAs, mRNAs, and non-coding RNAs, with implications for ribosome and mitochondrial function.