Jean‐François Mangin

Self-supervised representations reveal the genetic architecture of human cortical folding

The paper uses self-supervised deep learning representations of cortical folding to identify more genetic loci associated with cortical shape than classical morphometry in a large cohort.

Clinically Relevant Biomarkers of Alzheimers Disease Are Associated with Age and Cortical Atrophy in Chimpanzees (Pan troglodytes)

The paper examines age-related changes in Alzheimer's disease biomarkers and their association with cortical atrophy in chimpanzees, finding significant correlations between biomarkers and brain aging phenotypes.

Siibra: A software tool suite for realizing a Multilevel Human Brain Atlas from complex data resources

The paper introduces siibra, a software tool suite that integrates diverse brain data into a Multilevel Human Brain Atlas, enabling interoperable analysis and visualization.

FAST BOLD FMRI REVEALS THE SPATIOTEMPORAL COMPLEXITY OF NEUROVASCULAR COUPLING ALTERATIONS IN CEREBRAL SMALL VESSEL DISEASE

The paper uses fast BOLD fMRI to study neurovascular coupling in CADASIL patients, finding altered BOLD response amplitude and timing indicative of early neurovascular impairment.

Cortical folding patterns are encoded in the geometry of the unfolded neocortex.

This study shows that neocortical geometry at birth predicts adult cortical folding patterns and sulcal-gyral fate, suggesting geometry provides positional information alongside molecular signals.

On the typical development of the central sulcus in infancy: a longitudinal evaluation of its morphology and link to behaviour

This study longitudinally evaluates the morphology of the central sulcus in infants and its potential link to motor development.

A bipolar taxonomy of adult human brain sulcal morphology related to timing of fetalsulcation and trans-sulcal gene expression gradients

The paper constructs a sulcal phenotype network from MRI scans to identify two clusters of sulci related to developmental timing and gene expression gradients.

In vivo mapping of the deep and superficial whitematter connectivity in the chimpanzee brain

This study creates a new white matter connectivity atlas for chimpanzees and compares it to humans to understand primate brain evolution.

Structural basis of envelope and phase intrinsic coupling modes of the cerebral cortex

The paper investigates the relationship between intrinsic coupling modes (ICMs) in brain activity and structural connectivity in the ferret brain, showing strong correlations except when zero-lag synchronizations are removed.

Exploring the emergence of morphological asymmetries around the brain's Sylvian fissure: a longitudinal study of shape variability in preterm infants.

This study examines the longitudinal development of the Sylvian fissure's shape asymmetry in preterm infants, finding early encoding of asymmetry and left-hemisphere opercularization.

Genetic variations within human gained enhancer elements affect human brain sulcal morphology.

The paper identifies genetic variations in human gained enhancers that explain heritability of specific brain sulcal morphologies in the UK Biobank.

Shape variability of the central sulcus in the developing brain: a longitudinal descriptive and predictive study in preterm infants.

This study quantifies the shape variability of the central sulcus in preterm infants using MRI and identifies features predictive of motor outcomes at 5 years of age.

Genome-wide haplotype association study in imaging genetics using whole-brain sulcal openings of 16,304 UK Biobank subjects.

This study performs a genome-wide haplotype association analysis of brain sulcal openings in 16,304 UK Biobank subjects, finding haplotype analysis more sensitive than single-SNP approaches.

The reliability and heritability of cortical folds and their genetic correlations across hemispheres.

This study estimates the reliability and heritability of cortical folds using MRI data, finding moderate to high heritability for most sulcal metrics and regional variation in genetic influences.

Enhancer locus in ch14q23.1 modulates brain asymmetric temporal regions involved in language processing

The paper identifies an enhancer locus in 14q23.1 associated with brain asymmetry in regions involved in language processing, using UK Biobank and IMAGEN data.

Network analysis of whole-brain fMRI dynamics: A new framework based on dynamic communicability

This paper introduces a dynamic network framework for analyzing whole-brain fMRI data, showing functional communities merge over time and networks shift from segregated to integrated activity.

Increased and decreased superficial white matter structural connectivity in schizophrenia and bipolar disorder

This study investigates superficial white matter microstructure in schizophrenia and bipolar disorder using diffusion weighted imaging, finding altered fractional anisotropy in specific brain regions.

Comparison between diffusion MRI tractography and histological tract-tracing of cortico-cortical structural connectivity in the ferret brain

This study compares diffusion MRI tractography with histological tract-tracing in ferrets to assess the reliability of tractography algorithms in mapping cortico-cortical connectivity.

eQTL of KCNK2 regionally influences the brain sulcal widening: evidence from 15,597 UK Biobank participants with neuroimaging data

The paper identifies genetic variants influencing brain sulcal widening using UK Biobank data, finding an eQTL for KCNK2 associated with cortical atrophy and cognitive decline.