Yuting Lou

Paired-surface spatial mechanomics links tissue stiffness maps to spatial transcriptomics

Theca cell mechanosensing and regulation of follicular extracellular matrix during ovarian follicle development

This study investigates how theca cell mechanosensing and extracellular matrix properties regulate ovarian follicle development in mice.

Critical phenomenon underlies de novo luminogenesis during mammalian follicle development

The paper investigates the spatiotemporal dynamics of lumen formation in mammalian follicles, revealing a critical phenomenon involving fluid networks and cell death.

Stress anisotropy in 3D active curved structures

This paper develops a continuum framework to study stress anisotropy in 3D curved biological layers, showing how curvature and cell mechanics lead to irregular cellular shapes like scutoids.

Theca cell mechanics and tissue pressure regulate mammalian ovarian folliculogenesis

This study shows that theca cells regulate ovarian follicle growth through mechanical signaling and tissue pressure, affecting granulosa cell behavior and oocyte development.