Jean-François Rupprecht

The paper shows how stochastic dynamics and cytoskeletal regulation shape distinct neuronal morphologies in Drosophila mechanosensory neurons.

This study identifies fibrillar adhesions as the primary integrin complexes that respond to matrix topography, forming independently of focal adhesions.

This study identifies a multicellular actin star network in adult murine intestinal epithelium that maintains tissue stability and organization through mechanical and structural mechanisms.

This paper develops a continuum framework to study stress anisotropy in 3D curved biological layers, showing how curvature and cell mechanics lead to irregular cellular shapes like scutoids.

The paper identifies a titin-dependent biomechanical feedback mechanism that adjusts sarcomere structure to meet the functional demands of different insect muscle types.

The paper introduces a two-stage framework for detecting cell divisions in 2D and 3D time-lapse images using segmentation and regression models, achieving high accuracy with efficient architectures.

The paper investigates how deterministic and stochastic mechanisms shape dendritic branching in Drosophila neurons, finding that primary branches grow deterministically while secondary branches exhibit stochastic behavior influenced by geometric feedback.

The paper shows that embryonic geometry, not genetics, drives phenotypic variation in decanalized Drosophila embryos by shifting segmentation gene boundaries based on embryonic length.

The paper challenges current understanding of molecular motor force generation by showing that myosin filaments generate large reversible forces in cells through collective behavior.