Kristina A. Kigerl

Oral Bacterial Translocation Promotes Lung Dysbiosis and Infection Risk after Spinal Cord Injury

This study identifies the oral cavity as a source of lung dysbiosis after spinal cord injury and shows that targeted antibiotic delivery reduces infection risk.

Precision Prediction of Microbial Ecosystem Impact on Host Metabolism Using Genome-Resolved Metagenomics

The paper predicts microbial ecosystem impact on host metabolism using genome-resolved metagenomics, identifying key species and pathways involved in nitrogen balance and host health.

Disruption of the spinal cord-gut axis alters gut microbial dynamics and carbohydrate cross-feeding

This study shows that disrupting the spinal cord-gut axis alters gut microbial dynamics and carbohydrate cross-feeding, with interventions restoring health.

Spinal Cord Injury Imprints a Glucocorticoid-Driven Failure State in Hematopoietic Stem Cells

This paper shows spinal cord injury causes hematopoietic stem cells to enter a repressed state due to glucocorticoid surges, leading to long-term hematopoietic failure, which can be reversed by early glucocorticoid receptor blockade.

Targeting the Microbiome to Improve Gut Health and Breathing Function After Spinal Cord Injury

This paper shows that probiotic treatment after spinal cord injury improves gut health and respiratory function by reducing inflammation and enhancing neuronal regeneration.