Author

Tanja Natascha Fehm

Heinrich Heine University DüsseldorfORCID 0000-0002-4926-0108Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dieter NiederacheriD· 2 shared Hans J. NeubaueriD· 2 shared André FrankeniD· 1 shared Andrea Kulik· 1 shared Anna AbramovaiD· 1 shared Anna Sophie BerghoffiD· 1 shared Benedikt BrorsiD· 1 shared Berthold Gierke· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

Dieter NiederacherORCID

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Author profile →

3 papers

Recent·Most cited

Identification and characterization of tertiary lymphoid structures in brain metastases

Sadaf Shabbir Mughal, Yvonne Reiss, Jörg Felsberg, Lasse Meyer, Jadranka Macas, Silja Schlue, Tatjana Starzetz, Karl Köhrer, Tanja Natascha Fehm, Volkmar Müller, Katrin Lamszus, Dirk Schadendorf, Iris Helfrich, Harriet Wikman, Anna Sophie Berghoff, , Guido Reifenberger

The paper identifies tertiary lymphoid structures in brain metastases from different cancer types and links their presence to patient survival.

Acta Neuropathologica Communications · May 3, 2025Peer-reviewedCancer Biology

Development of a Bipyrimidineamide based α-Helix Mimetic Lead Compound for efficient Targeting of MDM2 in Triple-Negative Breast Cancer

Jasmin Linh On, Vitalij Woloschin, Franziska Gier, Jia‐Wey Tu, Sanil Bhatia, Thomas Lenz, Andrea Kulik, Kai Stühler, Dieter Niederacher, Hans J. Neubauer, Tanja Natascha Fehm, Thomas Kurz, Knud Esser

This study develops a bipyrimidineamide-based α-helix mimetic compound, VWK603, which effectively targets MDM2 in TNBC cells with lower toxicity than Nutlin-3a.

bioRxiv · Mar 2, 2024 · PreprintCancer Biology

ZeptoCTC - Sensitive Protein Analysis of True Single Cell Lysates using Reverse Phase Protein Arrays (RPPA)

Mahdi Rivandi, André Franken, Liwen Yang, Anna Abramova, Nadia Stamm, Jens Eberhardt, Berthold Gierke, Meike Beer, Tanja Natascha Fehm, Dieter Niederacher, Michael Pawlak, Hans J. Neubauer

ZeptoCTC is a single-cell protein analysis workflow that uses RPPA to measure protein expression and activation in CTCs, showing higher pAkt levels in mutated CTCs compared to wild-type.

bioRxiv · Sep 16, 2023 · PreprintMolecular Biology