Robert W. Harkness V

This study uses charge detection mass spectrometry to analyze DegP oligomerization states and client interactions, revealing new oligomer types and dynamic behavior.

The paper investigates how competing factors in biomolecular condensates modulate the rate of poly(A) RNA deadenylation by CNOT7, revealing concentration-dependent increases and diffusion-related decreases in enzymatic efficiency.

This study reveals the activation mechanism of human mitochondrial ClpP protease through structures showing how inhibitors induce an allosteric transition to the active state, with implications for cancer therapy.