Author

Lisa M. Smits

University of LuxembourgORCID 0000-0002-1912-4834Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Jens Christian SchwamborniD· 3 shared Silvia BologniniD· 3 shared Aleksandar RakovićiD· 1 shared Alexander SkupiniD· 1 shared Anna Sophia MonzeliD· 1 shared Christian JägeriD· 1 shared Christine KleiniD· 1 shared Eiichiro MoriiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Jens Christian SchwambornORCID

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3 papers

Recent·Most cited

NeuroscienceCell and Tissue ResearchPeer-reviewedJul 31, 2020

Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids

Lisa M. Smits, Stefano Magni, Kaoru Kinugawa…·Jens Christian Schwamborn

The paper uses single-cell RNA-sequencing to identify multiple neuronal cell types in human midbrain organoids, including dopaminergic, GABAergic, and glutamatergic neurons.

49 citations

humanscRNA-seq

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NeurosciencebioRxivPreprintOct 22, 2019

Parkinson’s disease phenotypes in patient specific brain organoids are improved by HP-β-CD treatment

Javier Jarazo, Kyriaki Barmpa, Isabel Rosety…·Jens Christian Schwamborn

This study shows that HP-β-CD treatment improves dopaminergic differentiation in PD patient-derived midbrain organoids by enhancing mitophagy.

14 citations

humanexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 19, 2017

In Vivo Phenotyping Of Parkinson-Specific Stem Cells Reveals Increased a-Synuclein Levels But No Spreading

Kathrin Hemmer, Lisa M. Smits, Silvia Bolognin, Jens Christian Schwamborn

This study transplants Parkinson's patient iPSC-derived neurons into mice, finding increased alpha-Synuclein levels but no spreading in the mouse brain.

1 citation

humanmouse

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