Zbigniew Mikulski

This study identifies binding dynamics as a key factor in enhancing germinal center responses to HIV immunogens, improving the efficiency of somatic hypermutation and bnAb precursor activation.

This study shows that combining SUMO E1 inhibition with TIGIT blockade enhances anti-tumor immunity in pancreatic cancer by reducing regulatory T cells and improving T cell reactivity.

The paper quantifies macrophage infiltration in pancreatic tissue of type 1 diabetes donors and finds increased infiltration and HLA-II expression in islet regions, suggesting a role in disease progression.

The paper maps the subcellular localization of PKA subunits in the retina, revealing distinct patterns and functional nonredundancy, with C{beta} localized to mitochondria and linked to neurodegenerative diseases.