Author

Catherine Au

University College LondonORCID 0000-0002-1923-9121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

David GemsiD· 3 shared Alexandre BenedettoiD· 2 shared Ann F. Gilliat· 2 shared Marina EzcurraiD· 2 shared Aihan ZhangiD· 1 shared Alexandra L. Petrache· 1 shared Brian H. K. ChaniD· 1 shared Carina C. KerniD· 1 shared

Activity by Year

2017-2024 · peak 1/yr

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10 top collaborators · 27 mutual co-author links

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3 shared papersGenetics

David GemsORCID

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3 papers

Recent·Most cited

Machine learning predicts lifespan and underlying causes of death in aging C. elegans

Carina C. Kern, Petru Manescu, Matt Cuffaro, Catherine Au, Aihan Zhang, Hongyuan Wang, Ann F. Gilliat, Marina Ezcurra, David Gems

The paper uses machine learning to predict lifespan and causes of death in aging C. elegans by analyzing senescent pathology and genetic factors.

bioRxiv · Mar 20, 2024 · PreprintGenetics

LFASS: Label-Free Automated Survival Scoring for High-Throughput Nematode Assays

Alexandre Benedetto, Timothée Bambade, Catherine Au, Jennifer M. A. Tullet, Jennifer L. Monkhouse, Hairuo Dang, Kalina Cetnar, Brian H. K. Chan, Filipe Cabreiro, David Gems

The paper introduces a label-free automated method to score nematode survival in high-throughput assays and finds an autophagy-dependent increase in acute stress resistance in early adulthood.

Aging Cell · Jul 16, 2019Peer-reviewedGenetics

Autophagy-dependent gut-to-yolk biomass conversion generates visceral polymorbidity in aging C. elegans

Marina Ezcurra, Alexandre Benedetto, Thanet Sornda, Ann F. Gilliat, Catherine Au, Qifeng Zhang, Sophie van Schelt, Alexandra L. Petrache, Yila de la Guardia, Shoshana Bar-Nun, Eleanor Tyler, Michael J. Wakelam, David Gems

This study identifies autophagy-mediated gut-to-yolk biomass conversion as a cause of visceral pathologies and polymorbidity in aging C. elegans, and shows that inhibiting this process extends lifespan.

bioRxiv · Dec 15, 2017 · PreprintPhysiology