Wote Amelo Rike

The paper shows that extracellular vesicles from healthy iPSCs can reverse Parkinson's disease-related deficits in human and mouse models.

This study shows that EVs from stem cells can rescue cellular and behavioral deficits in Shank3-deficient models of ASD.

This study identifies 31 commonly dysregulated genes across seven neurological disorders, enriched in brain ECM pathways, suggesting distinct ECM changes in disease states.

This paper explores the relationship between gastrointestinal issues and autism spectrum disorders, highlighting potential mechanisms and the need for further research.

This study investigates SLC1A4 mutations in human iPSC-derived neurons, revealing metabolic and synaptic deficits linked to amino acid transport dysfunction and neurodevelopmental disorders.

This paper identifies genetic signatures in lymphoblastoid cell lines associated with suicide risk in bipolar disorder patients using RNA sequencing and machine learning.

This study examines electrophysiological and gene expression changes in dopaminergic neurons from Parkinson's disease patients and those with GBA1 mutations, identifying synaptic dysfunction and ECM pathway dysregulation.