Ashwani Choudhary

The paper shows that extracellular vesicles from healthy iPSCs can reverse Parkinson's disease-related deficits in human and mouse models.

This study shows that EVs from stem cells can rescue cellular and behavioral deficits in Shank3-deficient models of ASD.

This study compares lithium-responsive and non-responsive bipolar disorder patients' GABAergic neurons, showing divergent excitability that drives network state shifts, potentially linked to mood episodes.

The paper compares genetic and cellular differences between autism and schizophrenia using GWAS and iPSC-derived neurons, finding shared SNPs and similar synaptic deficits.

This paper identifies genetic signatures in lymphoblastoid cell lines associated with suicide risk in bipolar disorder patients using RNA sequencing and machine learning.

This study compares neuronal phenotypes from monozygotic twins discordant for schizophrenia, finding differences in synaptic activity and neuronal maturation between affected and unaffected siblings.

The paper shows that cortical neurons from ASD-associated mutations exhibit early maturation and hyperexcitability compared to controls.

The paper investigates the role of nitric oxide in autism spectrum disorder, showing that targeting its production reverses ASD-like phenotypes in mouse models and human samples.

This paper reviews genomic studies and iPSC-based models of schizophrenia to summarize current progress in understanding its genetic basis and cellular mechanisms.