Ritu Nayak

This study investigates SLC1A4 mutations in human iPSC-derived neurons, revealing metabolic and synaptic deficits linked to amino acid transport dysfunction and neurodevelopmental disorders.

This paper identifies genetic signatures in lymphoblastoid cell lines associated with suicide risk in bipolar disorder patients using RNA sequencing and machine learning.

This study compares neuronal phenotypes from monozygotic twins discordant for schizophrenia, finding differences in synaptic activity and neuronal maturation between affected and unaffected siblings.

The paper shows that cortical neurons from ASD-associated mutations exhibit early maturation and hyperexcitability compared to controls.

This paper reviews genomic studies and iPSC-based models of schizophrenia to summarize current progress in understanding its genetic basis and cellular mechanisms.

The paper compares midbrain neurons from PD patients with mutations and sporadic PD, finding reduced synaptic activity and dysregulated extracellular matrix pathways as common features.