Cancer BiologyCellPeer-reviewed
Distinct Perception Mechanisms of BACH1 Quaternary Structure Degrons by Two F-box Proteins under Oxidative Stress
Shiyun Cao, Sheena Faye Garcia, Huigang Shi…·Ning Zheng
This study reveals how two F-box proteins, FBXO22 and FBXL17, recognize distinct structural features of the BACH1 BTB dimer under oxidative stress, leading to its ubiquitination and degradation.
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