Author

Sheena Faye Garcia

NYU Langone’s Laura and Isaac Perlmutter Cancer CenterORCID 0000-0002-2716-2638Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein structure· 1

Frequent Co-Authors

Beatrix M. UeberheideiD· 2 shared Gergely RónaiD· 2 shared Michele PaganoiD· 2 shared Sharon KaisariiD· 2 shared Yuki KitoiD· 2 shared Antonio MarzioiD· 1 shared Ellie I. JamesiD· 1 shared Haibin MaoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

Beatrix M. UeberheideORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cell BiologyeLifePeer-reviewedJan 19, 2026

GMCL1 Controls 53BP1 Stability and Modulates Taxane Sensitivity

Yuki Kito, Tania J González-Robles, Sharon Kaisari…·Michele Pagano

This study identifies GMCL1 as a negative regulator of the mitotic stopwatch pathway, showing it promotes 53BP1 degradation and reduces paclitaxel sensitivity in cancer cells.

DOI 10.7554/elife.106730.3

humanproteomics

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Cancer BiologyCellPeer-reviewedNov 5, 2024

Distinct Perception Mechanisms of BACH1 Quaternary Structure Degrons by Two F-box Proteins under Oxidative Stress

Shiyun Cao, Sheena Faye Garcia, Huigang Shi…·Ning Zheng

This study reveals how two F-box proteins, FBXO22 and FBXL17, recognize distinct structural features of the BACH1 BTB dimer under oxidative stress, leading to its ubiquitination and degradation.

47 citationstop 2%

humanprotein structure

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