Kun D. Huang

This study shows that the microbiome influences disease severity in CTLA-4 insufficient mice and humans by altering immune responses and promoting inflammation.

The paper investigates how dietary components and Enterobacteriaceae influence competition between Prevotellaceae and Bacteroidaceae in the gut microbiota, finding that Enterobacteriaceae enhance Prevotellaceae dominance under specific conditions.

This study identifies a small RNA, SrcF, essential for gut colonization of Segatella copri, regulated by complex carbohydrates and influenced by the human microbiome.

The paper compares microbiome composition and function across rheumatic diseases to identify microbial signatures predicting methotrexate response in RA and PsA.

Marker genes for 26,970 species-level genome bins, 4,992 defined only by metagenome-assembled genomes, let MetaPhlAn 4 quantify uncharacterized species and beat MetaPhlAn 3, mOTUs and Bracken on synthetic benchmarks.